Anti-LRP1 (N-terminal) antibody produced in rabbit

Descrição detalhada : LDL receptor-related protein 1 (LRP1), also known as 2-macroglobulin receptor, is a large endocytic receptor, widely expressed on the surface and intracellular membranes of various cells. LRP1 is encoded by the gene mapped to human chromosome 12q13.3. The encoded protein is a member of the LDL receptor family. LRP1 is synthesized in the endoplasmic reticulum as a single-chain 600 kDa type I transmembrane glycosylated precursor that is cleaved subsequently in the Golgi complex into two subunits of 515 kDa and 85 kDa. The 515 kDa N-terminal subunit remains attached to the membrane through noncovalent association with the smaller 85 kDa C-terminal subunit, which contains the transmembrane and cytoplasmic domains.
Sinónimos : Anti-A2MR; Anti-APOER; Anti-APR; Anti-Alpha-2-Macroglobulin receptor; Anti-Apolipoprotein E receptor; Anti-CD91; Anti-LRP; Anti-Low density lipoprotein receptor-related protein 1
Armazenamento : -20C
Embalagem : 1X200UL