5-Aza-2ʹ-Deoxycytidine – CAS 2353-33-5 – Calbiochem

Descrição detalhada : A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. Also available as a 100 mM solution in DMSO (Cat. No. 189826)., A cytosine analog that acts as a DNA methyltransferase inhibitor. Shown to restore mRNA and protein expression of caspase-8 and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) sensitivity of resistant cell lines. Also reported to enhance apoptosis induced by histone deacetylase (HDAC) inhibitors.
Sinónimos : 5-Aza-2?-Deoxycytidine - CAS 2353-33-5 - Calbiochem; 5-Aza-CdR, 5-Aza-dC, 2'-Deoxy-5-azacytidine, Decitabine
Fórmula molecula r: C8H12N4O4
Armazenamento : 2-8C
Embalagem : 1X25MG