Calcineurin Autoinhibitory Peptide, Cell-permeable – Calbiochem

REF : 207001-1MG
Marca : Sigma-Aldrich
Descrição :Calcineurin Autoinhibitory Peptide, Cell-permeable - Calbiochem The Calcineurin Autoinhibitory Peptide, Cell-permeable controls the biological activity of Mn2+-stimulated calcineurin activity. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable peptide that consists of the calcineurin (CaN) autoinhibitory domain (AID) fused to a poly-arginine-based protein transduction doamin (11R) and acts as an inhibitor of CaN phosphatase activity. Reported to block CaN-dependent NFAT nuclear translocation and NFAT promoter activity in neurons. Also reported to protect neuronal cells from glutamate-induced cell death., A cell-permeable peptide that is composed of the calcineurin (CaN) autoinhibitory domain (AID) fused to a poly-arginine-based protein transduction domain (11R) and acts as an inhibitor of CaN phosphatase activity. Blocks CaN-dependent NFAT nuclear translocation and NFAT promoter activity in neurons. Protects neuronal cells from glutamate-induced cell death.
Sinónimos : Calcineurin Autoinhibitory Peptide, Cell-permeable - Calbiochem; 11R-CaN-AID, Ac-RRRRRRRRRRRGGGRMAPPRRDAMPSDA-NH₂
Fórmula molecula r: C137H251N71O34S2
Armazenamento : -20C
Embalagem : 1X1MG