eEF2K Inhibitor, A-484954 – CAS 142557-61-7 – Calbiochem

REF : 324516-10MG
Marca : Sigma-Aldrich
Descrição :eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem The eEF2K Inhibitor, A-484954, also referenced under CAS 142557-61-7, controls the biological activity of eEF2K Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable pyrido-pyrimidinedione derivative that acts as a highly potent and selective inhibitor of eukaryotic elongation factor-2 kinase (eEF2K) (IC50= 280 nM). Exhibits very little activity against a broad panel of serine/threonine and protein tyrosine kinases. Inhibits eEF2 phosphorylation in multiple cell lines tested without affecting the net eEF2 levels. At concentration where it inhibits eEF2K activity, it has no effect on the proliferation of cancer cell lines.
Sinónimos : eEF2K Inhibitor, A-484954 - CAS 142557-61-7 - Calbiochem; 7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide, Eukaryotic elongation factor-2 kinase inhibitor, A-484954
Fórmula molecula r: C13H15N5O3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG