Factor I, Human

Descrição detalhada : Native factor I from human serum. Glycoprotein composed of two non-identical disulfide-bonded subunits of M.W. of ~50 kDa (alpha) and ~38 kDa (beta). Present in normal human serum at about 34 µg/ml. A serine protease that requires protein cofactor in order to effect substrate cleavage. Either Factor H or Factor I mediates cleavage of C3b. C4-binding protein or complement receptor CR1 can function as the cofactor required for Factor I mediated cleavage of C4b., Native factor I from human serum. Glycoprotein composed of two non-identical disulfide-bonded subunits of M.W. of 50 kDa (alpha) and 38 kDa (beta). Present in normal human serum at about 34 µg/ml. A serine protease that requires protein cofactor in order to effect substrate cleavage. Thus, either Factor H or Factor I mediates cleavage of C3b. C4-binding protein or complement receptor CR1 can function as the cofactor required for Factor I-mediated cleavage of C4b.
Sinónimos : C3b/C4b Inactivator
Armazenamento : -70C
Embalagem : 1X250UG