GSK-3 Inhibitor IX, Control, MeBIO – CAS 710323-61-8 – Calbiochem

REF : 361556-1MG
Marca : Sigma-Aldrich
Descrição :GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem The GSK-3 Inhibitor IX, Control, MeBIO, also referenced under CAS 710323-61-8, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as an inactive control for Cdk1/cyclin B, Cdk5/p25, and GSK-3alpha/beta (IC50 >92 µM for Cdk1/cyclin B, >100 µM for Cdk5/p25, and GSK-3alpha/beta). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties., A cell-permeable N-methylated analog of GSK-3 Inhibitor IX, BIO (Cat. No. 361550) that serves as a relevant kinase inactive control (IC50 >92 µM for Cdk1/B, >100 µM for Cdk5/p25, and GSK-3alpha/beta). Acts as a potent ligand for aryl hydrocarbon receptor (AhR; EC50 = 20 nM and 93 nM for yeast and hepatoma reporter systems, respectively) and displays antiproliferative properties.
Sinónimos : GSK-3 Inhibitor IX, Control, MeBIO - CAS 710323-61-8 - Calbiochem; 1-Methyl-BIO
Fórmula molecula r: C17H12BrN3O2
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X1MG