L-N⁵-(1-Iminoethyl)ornithine, Dihydrochloride – CAS 159190-44-0 – Calbiochem

Descrição detalhada : A cell-permeable, more potent inhibitor of endothelial nitric oxide synthase (eNOS; IC50 = 500 nM) compared to other arginine analogs such as L-NAME (Cat. No. 483125) and L-NMMA (Cat. No. 475886). Inhibits acetylcholine-induced relaxation of rat aorta rings (IC50 = 2 µM) and causes a dose-dependent increase in mean arterial blood pressure in the rat (EC50 = 19.5 mg/kg)., Cell permeable. Approximately five times more potent as an inhibitor of endothelial nitric oxide synthase (IC50 = 500 nM) than other arginine analogs, such as L-NAME (Cat. No. 483125) and L-NMMA (Cat. No. 475886). Inhibits acetylcholine induced relaxation of rat aorta rings (IC50 = 2 µM) and causes a dose-dependent increase in mean arterial blood pressure in the rat (EC50 = 19.5 mg/kg).
Sinónimos : L-N?-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem; L-NIO, 2HCl
Fórmula molecula r: C7H15N3O2 · 2HCl
Armazenamento : -20C
Embalagem : 1X20MG