InSolution KN-93 – CAS 139298-40-1 – Calbiochem

Descrição detalhada : A cell-permeable, competitive inhibitor of Ca2+/calmodulin-dependent protein kinase II (Ki = 370 nM). Selectively binds to the Calmodulin (CaM) binding site of the enzyme and prevents the association of CaM with CaM Kinase II. Inhibits glucose-induced and forskolin-stimulated insulin release from isolated pancreatic islets. Has no significant effect on protein kinase A activity. Induces G1 cell cycle arrest and apoptosis in NIH 3T3 cells.
Sinónimos : InSolution KN-93 - CAS 139298-40-1 - Calbiochem
Fórmula molecula r: C26H29ClN2O4S
Armazenamento : -20C
Embalagem : 1X1MG