Myosin Light Chain Kinase Inhibitor Peptide 18 – Calbiochem

Descrição detalhada : A highly basic, cell-permeable, nonapeptide that acts as a selective Myosin Light Chain Kinase (MLCK) inhibitor (IC50 = 50 nM). The inhibition is competitive with respect to the peptide substrate (Ki = 52 nM) and displays a mixed mode of inhibition with respect to ATP. Does not interfere with kinase activation by calmodulin (CaM), nor does it inhibit the activities of CaMKII and PKA., A highly basic, cell-permable, nonapeptide that acts as a selective myosin light chain kinase (MLCK) inhibitor (IC50 = 50 nM). Does not block calmodulin (CaM) or inhibit the kinase activities of Ca2+/calmodulin kinase II (CaMKII) or protein kinase A (PKA). Inhibition is competitive with respect to substrate (Ki = 52 nM). Displays mixed mode inhibition with respect to ATP.
Sinónimos : Myosin Light Chain Kinase Inhibitor Peptide 18 - Calbiochem; H-RKKYKYRRK-NH?, MLCK Inhibitor Peptide 18, MLCK Inhibitor IV; MLCK Inhibitor Peptide 18, H-RKKYKYRRK-NH?, MLCK Inhibitor IV
Fórmula molecula r: C60H105N23O11
Armazenamento : -20C
Embalagem : 1X5MG