NDGA – CAS 500-38-9 – Calbiochem

REF : 479975-250MG
Marca : Sigma-Aldrich
Descrição :NDGA - CAS 500-38-9 - Calbiochem A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC?? = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC?? = 100 µM).
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Descrição detalhada : A cell-permeable, antioxidant and a selective lipoxygenase (LO) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LO, 12-LO, and 15-LO, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss 3T3 cells., A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss/3T3 cells. A powerful hydroxy radical quencher.
Sinónimos : NDGA - CAS 500-38-9 - Calbiochem; Nordihydroguaiaretic Acid
Fórmula molecula r: C18H22O4
Armazenamento : 10-30C
Embalagem : 1X250MG