Pterostilbene, Pterocarpus marsupium – CAS 537-42-8 – Calbiochem

Descrição detalhada : A cell-permeable methoxylated analog of Resveratrol (Cat. No. 554325) that displays antioxidant, antiproliferative, and hypoglycemic properties. Moderately inhibits COX-1 and -2 activities (IC50 = 19.8 µM and 83.9 µM) respectively, induces apoptosis in HL60 cells (IC50 = 70 µM), prevents DMBA-induced preneoplastic lesions (ED50 = 4.8 µM) and decreases plasma glucose level in streptozotocin-induced diabetic rats comparable to that of Metformin., A cell-permeable methoxylated analog of Resveratrol (Cat. No. 554325) that displays antioxidant, anti-proliferative, and hypoglycemic properties. Appears to be a better free radical scavenger than Trolox (Cat. No. 64847). Moderately inhibits COX-1 & COX-2 activities (IC50 = 19.8 µM & 83.9 µM, respectively) and induces apoptosis in HL60 cells (IC50 = 70 µM). Also prevents DMBA-induced pre-neoplastic lesions (ED50 = 4.8 µM). Reported to decrease plasma glucose levels in streptozotocin-induced diabetic rats comparable to that of Metformin.
Sinónimos : Pterostilbene, Pterocarpus marsupium - CAS 537-42-8 - Calbiochem; trans-3,5-Dimethoxy-4?-hydroxystilbene
Fórmula molecula r: C16H16O3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG