Phalloidin-Atto Rho6G

Descrição detalhada : Atto Rho6G is a novel fluorescent label that belongs to the class of Rhodamine dyes. It shows a strong absorption, extraordinary high fluorescence quantum yield, high thermal and photostability, and a very little triplet formation. Atto Rho6G is moderately hydrophilic.Phalloidin is a fungal toxin isolated from the poisonous mushroom Amanita phalloides. Its toxicity is attributed to the ability to bind F-actin in liver and muscle cells. As a result of binding phalloidin, actin filaments become strongly stabilized. Phalloidin has been found to bind only to polymeric and oligomeric forms of actin, and not to monomeric actin. The dissociation constant of the actin-phalloidin complex has been determined to be on the order of 3 x 10-8. Phalloidin differs from amanitin in rapidity of action; at high dose levels, death of mice or rats occurs within 1 or 2 hours.
Armazenamento : -20C
Embalagem : 1X10NMOL