GW4869

Descrição detalhada : GW4869 is a commonly used pharmacological agent, which inhibits exosome generation. It blocks ceramide-mediated inward budding of multivesicular bodies (MVBs) and the release of mature exosomes from MVBs. GW4869 exhibits cytotoxicity to phosphatidylserine-expressing myeloma cells. It inhibits the secretion of IFN (interferon)-? by plasmacytoid dendritic cells (pDCs).
Sinónimos : N,N'-Bis[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-3,3'-p-phenylene-bis-acrylamide dihydrochloride
Fórmula molecula r: C30H28N6O2 · 2HCl
Armazenamento : 2-8C
Embalagem : 1X5MG