Fibronectin human

Descrição detalhada : Fibronectin (FN) is a glycoprotein with 5-9% carbohydrates present as N- and O-linked oligosaccharides. It belongs to the ligand glycoprotein family. The FN gene is localized to human chromosome 2q35. FN exists as two major isoforms, plasma-based soluble and extracellular matrix (ECM)-based insoluble form. FN is a multidomain protein and comprises repeats of FNI, FNII and FNIII repeats. It also has fibrin-binding sites and exists as a dimer. Alternative splicing of the FN1 gene leads to the generation of many isoforms. Recombinant human fibronectin is expressed in human 293 cells as a glycoprotein with a calculated molecular mass of 259.5 kDa. This protein is manufactured in human cells using an all-human production system with no serum. The human cells expression system allows human-like glycosylation and folding, and often supports better stability of the protein in culture.
Sinónimos : Fibronectin; CIG; Cold-insoluble globulin; FN
Armazenamento : -20C
Embalagem : 1X200UG