Cholesterol
REF : C3045-5G
Marca : Sigma-Aldrich
Descrição :Cholesterol powder, BioReagent, suitable for cell culture, >=99%
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Categoria : Cell Culture - Commonly Used
Descrição detalhada : Cholesterol, a major sterol is the precursor for steroid hormones, bile acid and vitamin in mammals and coordinates endocytosis. It complexes with protein to form lipoproteins for transport in blood. It exists either as high-density lipoprotein (HDL) or low-density lipoprotein (LDL). HDL also called good cholesterol has less lipid content. LDL or bad cholesterol has high lipid content. Statin inhibition of HMG-CoA reductase enzyme in the cholesterol biosynthesis pathway controls elevated cholesterol levels in atherosclerosis and hypercholesterolemia. Low levels of cholesterol results in hypothyroidism, familial hypobetalipoproteinemia and liver disease. Imbalance of cholesterol homeostasis and intracellular cholesterol levels play a key role in cancer development. High cholesterol levels favor breast cancer progression.
Sinónimos : 3beta-Hydroxy-5-cholestene; 5-Cholesten-3beta-ol
Fórmula molecula r: C27H46O
Armazenamento : -20C
Embalagem : 1X5G
Sinónimos : 3beta-Hydroxy-5-cholestene; 5-Cholesten-3beta-ol
Fórmula molecula r: C27H46O
Armazenamento : -20C
Embalagem : 1X5G
