Monoclonal Anti-Connexin-43 antibody produced in mouse

REF : C8093-.2ML
Marca : Sigma-Aldrich
Descrição :Monoclonal Anti-Connexin-43 antibody produced in mouse clone CXN-6, ascites fluid
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Descrição detalhada : The 43 kDa connexin protein (connexin-43, Cx43) belongs to the a-type (group II) subfamily of connexin proteins. It is expressed in most tissues, even though the pattern of expression may differ in various cell types. For example, in the brain it is found in astrocytes, ependyma and leptomeninges but not in neurons, oligodendrocytes and pinealocytes; in the liver it is present in Ito cells but not hepatocytes. , Monoclonal Anti-Connexin-43 (mouse IgM isotype) is derived from the CXN-6 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Connexin 43 (Cx43) is also known as GJA1 (gap junction protein alpha 1). The structure of connexin molecules includes a cytoplasmic N-terminal region, four transmembrane domains, two extracellular loops and a C-terminal cytoplasmic tail of varying length.
Sinónimos : Anti-AVSD3; Anti-CMDR; Anti-CX43; Anti-EKVP; Anti-EKVP3; Anti-GJAL; Anti-HLHS1; Anti-HSS; Anti-ODDD; Anti-PPKCA
Armazenamento : -20C
Embalagem : 1X.2ML