Anti-TXNRD1 antibody produced in mouse

Descrição detalhada : This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. (provided by RefSeq)
Sinónimos : Anti-GRIM-12; Anti-MGC9145; Anti-TR; Anti-TR1; Anti-TRXR1; Anti-TXNR
Armazenamento : -20C
Embalagem : 1X50UG