InSolution PP2 – Calbiochem

REF : 529576-1MG

Marca : Sigma-Aldrich

Descrição :InSolution PP2 - Calbiochem InSolution PP2, 172889-27-9, is a 10 mM solution of PP2 (Cat. No. 529573) in DMSO. A potent, reversible, ATP-competitive, inhibitor of the Src family of protein tyrosine kinases.
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Categoria : Small Molecules

Descrição detalhada : A potent and selective inhibitor of the src family of tyrosine kinases. Its action is similar to PP1. Selectively inhibits p56lck (IC50 = 4 nM), p59fynT (IC50 = 5 nM), and Hck (IC50 = 5 nM) compared to other tyrosine kinases, such as EGF-R (IC50 = 480 nM), JAK2 (IC50 >50 µM) or ZAP-70 (IC50 >100 µM). Also potently inhibits anti-CD3-stimulated tyrosine phosphorylation of human T cells (IC50 = 600 nM).
Sinónimos : InSolution PP2 - Calbiochem
Fórmula molecula r: C15H16ClN5
Armazenamento : -20C
Embalagem : 1X1MG