PTP Inhibitor IV – CAS 329317-98-8 – Calbiochem

REF : 540211-10MG
Marca : Sigma-Aldrich
Descrição :PTP Inhibitor IV - CAS 329317-98-8 - Calbiochem The PTP Inhibitor IV, also referenced under CAS 329317-98-8, controls the biological activity of PTP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : An uncharged, 1,4-di-substituted, phenyl-linked, bis-trifluoromethylsulfonamido (TFMS) phosphate mimetic that acts as a potent, reversible, substrate competitive, active-site-directed inhibitor of protein tyrosine phosphatases (PTP). Reported to inhibit SHP-2 (IC50 = 1.8 microM), PTP1B (IC50 = 2.5 microM), PTP-ε (IC50 = 8.4 microM), PTP-Meg-2 (IC50 = 13 microM), PTP-ς (IC50 = 20 microM), PTP-β (IC50 = 6.4 microM), and PTP-micro (IC50 = 6.7 microM)., An uncharged, 1,4-di-substituted, phenyl-linked bis-trifluoromethylsulfonamido (TFMS) phosphate mimetic that acts as a potent, reversible, competitive, and active-site directed inhibitor of protein tyrosine phosphatases (PTP; IC50 = 1.8, 2.5, 8.4, 13, 20, 6.4, and 6.7 microM for SHP-2, PTP1B, PTP-ε, PTP-Meg-2, PTP-ς, PTP-β, and PTP-micro, respectively).
Sinónimos : PTP Inhibitor IV - CAS 329317-98-8 - Calbiochem; bis(4-Trifluoromethylsulfonamidophenyl)-1,4-diisopropylbenzene, Protein Tyrosine Phosphatase Inhibitor IV
Fórmula molecula r: C26H26F6N2O4S2
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG