RNA Polymerase III Inhibitor – CAS 577784-91-9 – Calbiochem

REF : 557403-10MG
Marca : Sigma-Aldrich
Descrição :RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC?? = 27 and 32 µM for human and S. cerevisiae RNA Pol III, respectively).
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Descrição detalhada : A cell-permeable inhibitor of RNA polymerase III (RNA Pol III) (IC50 = 27 µM for human RNA Pol III and 32 µM for Saccharomyces cerevisiae RNA Pol III). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription., A cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory activity against RNA Polymerase III (IC50 = 27 and 32 µM for human and S. cerevisiae RNA Pol III, respectively). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. Also available as a 25 mM solution in DMSO (Cat. No. 557404).
Sinónimos : RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem; ML-60218, N-[1-(3-(5-Chloro-3-methylbenzo[b]thiophen-2-yl-1-methyl-1H-pyrazol-5-yl)]-2-chlorobenzenesulfonamide
Fórmula molecula r: C19H15Cl2N3O2S2
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG