D,L-Sulforaphane – CAS 4478-93-7 – Calbiochem

Descrição detalhada : An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture. Shown to be an effective agent in prevention of chemically-induce mammary tumors in rats. Also shown to inhibit the phase I cytochrome P450 isoenzymes 2E1 and IA2 that have been associated with the activation of carcinogens. The induction of phase II enzymes is mediated by the mitogen-activated protein kinase (MAPK) pathway., An isothiocyanate isolated from broccoli that acts as a potent inducer of phase II detoxifying enzymes in mouse tissues and murine hepatoma cells in culture. It has been shown to be an effective agent in prevention of chemically-induced mammary tumors in rats. It also inhibits the phase I cytochrome P450 isoenzymes 2E1 and IA2 which have been associated with the activation of carcinogens. The induction of phase II enzymes is mediated by mitogen-activated protein kinase (MAPK) pathway.
Sinónimos : D,L-Sulforaphane - CAS 4478-93-7 - Calbiochem; 1-Isothiocyanato-4-(methylsulfinyl)butane, R,S-Sulforaphane
Fórmula molecula r: C6H11NOS2
Armazenamento : -20C
Embalagem : 1X25MG