Syk Inhibitor IV, BAY 61-3606 – CAS 732938-37-8 – Calbiochem

REF : 574714-2MG
Marca : Sigma-Aldrich
Descrição :Syk Inhibitor IV, BAY 61-3606 - CAS 732938-37-8 - Calbiochem The Syk Inhibitor IV, BAY 61-3606, also referenced under CAS 732938-37-8, controls the biological activity of Syk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable imidazopyrimidine compound that acts a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (IC50 = 10 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src even at concentrations as high as 4.7 µM. Shown to inhibit Syk-mediated cellular functions in vitro and exhibit good oral bioavailability and in vivo effacacy in the treatment of various allgery and asthma conditions in rat models.
Sinónimos : Syk Inhibitor IV, BAY 61-3606 - CAS 732938-37-8 - Calbiochem; 2-(7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino)-nicotinamide, HCl, BAY 61-3606
Fórmula molecula r: C20H18N6O3 · xHCl · yH2O
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X2MG