InSolution Trichostatin A, Streptomyces sp. – Calbiochem

Descrição detalhada : A potent and reversible inhibitor of histone deacetylase. Blocks cell cycle progression at the G1 phase in HeLa cells and induces a 12-fold increase in intracellular levels of gelsolin. Induces reversion of oncogenic ras-tranformed NIH 3T3 cells to a normal morphology. Inhibits IL-2 gene expression (IC50 = 73 nM) in Jurkat cells and shows immunosuppressive activity in a mouse model.
Sinónimos : InSolution Trichostatin A, Streptomyces sp. - Calbiochem; 4,6-Dimethyl-7-[p-dimethylaminophenyl]-7-oxahepta-2,4-dienohydroxamic Acid, HDAC Inhibitor IX, TSA
Fórmula molecula r: C17H22N2O3
Armazenamento : -20C
Embalagem : 1X500UG