Anti-c-Myc antibody, Mouse monoclonal

REF : M4439-100UL
Marca : Sigma-Aldrich
Descrição :Anti-c-Myc antibody, Mouse monoclonal clone 9E10, purified from hybridoma cell culture
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Descrição detalhada : The mouse Anti-c-MYC monoclonal antibody recognizes an epitope located within a sequence (EQKLISEEDL) of the product of the human oncogene c-myc., c-Myc (v-myc avian myelocytomatosis viral oncogene homolog) is a transcription factor, which is coded by MYC gene. It was first described as a homolog of an avian retroviral oncogene. It belongs to the family of transcription factors which are characterized by basic region helix-loop-helix/leucine zipper. Along with N-Myc and L-Myc, it forms the MYC proto-oncogene family. It forms a heterodimer with MAX, and this heterodimer binds to the E-boxes/CACGTG sequence motif on DNA. This gene is localized to human chromosome 8q24.
Sinónimos : Anti-c-Myc
Armazenamento : -20C
Embalagem : 1X100UL