Anti-Fibulin-5 Antibody

REF : AB6065
Marca : Sigma-Aldrich
Descrição :Anti-Fibulin-5 Antibody from rabbit, purified by affinity chromatography
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Descrição detalhada : Fibulin-5 (also known as EVEC/DANCE) is an extracellular matrix protein. Fibulin-5 is most commonly found in blood vessels and cardiac valves during embryogenesis and in adult tissue that contains elastic fibers like the skin, lungs, uterus and aorta. Fibulin-5 travels to the surface of the elastic fibers and its activity is dependent on calcium. Fibulin-5 seems to work as a scaffold protein that facilitates the binding of the elastic fibers to cells and the formation of the elastic fibers themselves. Mutations of fibulin-5 have been associated with age-related macular degeneration (AMD) and cutis laxa (CL).
Sinónimos : Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA