Anti-PRDM12 Antibody

Descrição detalhada : Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and the founding member of the PR domain family. PRDM12 (PR domain zinc finger protein 12) also acts as a tumor suppressor and is linked to the pathogenesis of chronic myeloid leukemia. PRDM12 is also thought to play a role in transcriptional regulation.
Sinónimos : PR domain zinc finger protein 12, PR domain-containing protein 12, arg methyltransferase, arginine methyltransferase, PR domain family
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA