Fmoc-Glu(O-2-PhiPr)-OH

Descrição detalhada : Quasi-orthogonally-protected Glu derivative. The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS [2] or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(Mtt) and Glu(O-2-PhiPr) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.The product number for this product was previously 04-12-1199.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Sinónimos : Fmoc-Glu(O-2-PhiPr)-OH; N-alpha-Fmoc-L-glutamic acid gamma-2-phenylisopropyl ester
Fórmula molecula r: C29H29NO6
Armazenamento : 15-25C
Embalagem : 1X1EA