HMPB-MBHA resin

Descrição detalhada : This support consists of MBHA resin functionalized with Riniker′s hyperacid-labile 4-hydroxymethyl-3-methoxyphenoxybutyric acid linker [1].This hyperacid-sensitive resin is a useful tool for the Fmoc SPPS of protected peptide acid fragments.Attachment of carboxylic acids is normally achieved by DMAP catalyzed esterification with the appropriate symmetrical anhydride, or by using 2,6-dichlorobenzoyl chloride/pyridine [2] or MSNT/Melm activation [3, 4, 5].Detachment of these functionalities can be effected by treatment with 1-5% TFA in DCM.The product number for this product was previously 01-64-0036.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Sinónimos : 4-Hydroxymethyl-3-methoxyphenoxybutyric acid MBHA resin
Armazenamento : 2-30C
Embalagem : 1X1EA