Anti-PDGF-AA Antibody

Descrição detalhada : Platelet-Derived Growth Factor (PDGF) is a dimer of A (17 kDa) and B (14 kDa) chains (AA, AB, or BB). Its receptors are transmembrane receptor tyrosine kinases, PDGF Receptors type A and B. The type A PDGF receptor binds all three PDGFs with high affinity, whereas the type B PDGF receptor is selective for PDGF-BB. PDGF signals as a growth and survival factor, as it is a potent activator of the PI3 Kinase pathway. PDGF signaling appears to play an essential role in the development of tumors of glial origin.
Sinónimos : Platelet-derived growth factor alpha, Platelet-derived growth factor alpha chain, Platelet-derived growth factor alpha polypeptide
Armazenamento : -20°C
Embalagem : 1X1EA