Milli-Mark(R) Anti-CD56-PE Antibody, clone C5.9

Descrição detalhada : CD56 is a membrane glycoprotein which has multiple isoforms generated by alternative splicing from a single gene located on chromosome 11 (Costa, 1997). The core polypeptide is the 140 kDa isoform which can be variably glycosylated to produce mature species. The predominant isoform in NK and T cells is the transmembrane-anchored 140 kDa protein. In tissues, CD56 antigen is found in the cerebellum and cortex of the brain, and at neuromuscular junctions. This molecule is identical to the 140 kDa isoform of the neuronal cell adhesion molecule (N-CAM) (Poggi, 2002; Lanier, 1989). Additionally, CD56 is also present in certain large granular lymphocyte leukemias, small cell lung carcinomas, neural-derived tumors, myelomas, and myeloid leukemias (Poggi, 2002).
Sinónimos : Neural cell adhesion molecule 1, NCAM-1
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA