IL-36 BETA human

Descrição detalhada : IL-36beta is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36beta signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36beta also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3.
Sinónimos : IL-1 eta; IL-1F8; IL-1H2
Armazenamento : -20C
Embalagem : 1X10UG