IL-36 GAMMA human

Descrição detalhada : IL-36gamma is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36gamma signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36gamma also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells.
Sinónimos : IL-1epsilon; IL-1F; IL-1H1
Armazenamento : -20C
Embalagem : 1X10UG