Anti-Neuronal pentraxin 1 Antibody

Descrição detalhada : Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX1(Neuronal Pentraxin 1) a 432aa protein in mouse and rat, 430aa in human (chr 17q25). It mediates the uptake of degraded synaptic material which could play an important role in synaptic remodeling, expressed in brain.
Sinónimos : NPX1
Armazenamento : -20°C
Embalagem : 1X1EA