Anti-RhoG Antibody, clone 1F3 B3 E5

Descrição detalhada : RhoG (ARGH) is a member of the Ras super-family of small G-proteins and a member of the Rac subfamily of Rho Family of GTPases. RhoG is a small G-protein (GTPase) who is activated by a GEF (guanine nucleotide exchange factor). The GEF displaces GDP from the binding site of RhoG and allows GTP to bind in it place rendering the protein active. This active RhoG binds downstream effector molecules that include ELMO and DOCK180. RhoG then cleaves GTP to GDP making it inactive. RhoG is believed to be crucial for integrin-mediated Rac activation and cell spreading. RhoG is believed to be active upstream of Rac and work independently of Rac.
Sinónimos : ARHG, RHOG ras homolog gene family, member G (rho G), MGC125835, MGC125836
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA