Anti-p62 (Sequestosome-1) Antibody, clone 11C9.2

Descrição detalhada : p62 is also known as sequestosome-1, and is a 62 kDa ras-GAP associated protein. p62 is thought to bind to src-family tyrosine kinases and may also provide a linker action for activated src-family kinases with their downstream effectors. p62 has an RNA-binding region and may have RNA-binding ability. p62 is associated with activation of transcription factor NF-kappaB, involved in cell differentiation, immune response and potassium channel regulation. p62 has recently been linked to extrinsic apoptosis and may be a key player in tumorigenesis.
Sinónimos : sequestosome 1, EBI3-associated protein of 60 kDa, Paget disease of bone 3, phosphotyrosine independent ligand for the Lck SH2 domain p62, oxidative stress induced like, EBI3-associated protein p60, Phosphotyrosine-independent ligand for the Lck SH2 doma
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA