Anti-Thyroid Hormone Receptor beta-1 Antibody

Descrição detalhada : Thyroid hormone receptor beta-1 operates as a hormone-dependent transcriptional regulator that binds DNA sequences and is activated by 3,5,3'-l-triiodothyronine (T3). Thyroid hormone receptor beta-1 is important in vertebrate development, specifically in developing limbs and face. 9-cis-retinoic acid receptor (RXR) and retinoic acid receptor (RAR) receptor families are often associated with thyroid hormone receptor beta-1 and form homodimers and heterodimers. Mutations in thyroid hormone receptor beta-1 have been associated with general resistance to thyroid hormones which tend to cause significant behavioral abnormalities. Recent research has linked thyroid hormone receptor beta-1 to tumor suppression, where the receptor has commonly been found to be disrupted in the occurrence of cancer.
Sinónimos : Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2, c-erbA-2, c-erbA-beta
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA