Anti-Sarcolipin Antibody

Descrição detalhada : Sarcolipin (SLN) is a multidomain protein containing lumenal, cytoplasmic, and transmembrane domains. It is found in the membrane of the sarcoplasmic/endoplasmic reticulum of cardiac cells, and is involved in maintaining calcium homestasis underlying muscle contractility in the heart. Sarcoplipin achieves these effects through its regulation of the sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a), a calcium transport protein that actively pumps calcium from the cytoplasm into the sarcoplasmic reticulum, resulting in relaxation of the heart muscles. Sarcolipin may also interact with phospholamban, and may contribute to heart failure.
Sinónimos : Sarcopolin
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA