beta-NGF Protein, Human Recombinant Animal Free

Descrição detalhada : Product Source: E. coli, Nerve Growth Factor (beta-NGF) is a well characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF has also been shown to have biological effects on nonneuronal tissues. beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues). The three disulfide bonds are required for biological activity.
Sinónimos : Nerve Growth Factor, NGF, BNGF, Beta NGF
Armazenamento : -20°C
Embalagem : 1X1EA