Anti-EZH1 Antibody

REF : ABE281
Marca : Sigma-Aldrich
Descrição :Anti-EZH1 Antibody from rabbit, purified by affinity chromatography
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Descrição detalhada : Polycomb protein group complexes are responsible for the regulation of hundreds of genes in mammals and insects. These proteins are responsible for the assembly and packaging of chromatin and for the induction of methylation on Histone H3. EZH1 is the catalytic subunit of the PRC2/EED-EZH1 complex. This complex methylates Lys-27 of histone H3, which leads to transcriptional repression of the affected target gene. EZH1 is required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in maintaining the identity of embryonic stem cells.
Sinónimos : Histone-lysine N-methyltransferase EZH1, ENX-2, Enhancer of zeste homolog 1
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA