Anti-dimethyl-Histone H3 (Lys79) Antibody, clone NL59, Trial Size, rabbit monoclonal

Descrição detalhada : Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Dimethylation of Lys79 on histone H3 is associated with active gene transcription and is a marker for euchromatin. Histone H3 is methylated on Lys79 by the histone methyltransferase Dot1L.
Sinónimos : H3K79me2, Histone H3 (di methyl K79)
Armazenamento : -20°C
Embalagem : 1X1EA