Anti-phospho-MLKL (Ser358) Antibody Set

Descrição detalhada : This phospho-MLKL (Ser358) antibody set contains one vial of phospho-MLKL (Ser358) antibody and one vial of MLKL "Total" antibody. RECOMMENDED USAGE:It is recommended to first perform immunoprecipitation on your sample using the non-phosphorylated MLKL antibody for "total" MLKL protein isolation (see protocol section on page 2 of the Certificate of Analysis); then use the immunoprecipitated sample to detect the phosphorylated protein using the phospho-MLKL (Ser358) antibody via western blot., Mixed lineage kinase domain-like protein (MLKL) is required for the execution of programmed necrosis. MLKL is a cell-permeable acrylamide compound that inhibits human, but not murine, MLKL adaptor function via covalent modification of Cys86. MLKL prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with further downstream effectors.
Sinónimos : Mixed lineage kinase domain-like protein, MLKL
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA