AC16 Human Cardiomyocyte Cell Line

Descrição detalhada : AC16 Human Cardiomyocyte Cell Line is a proliferating cell line that was derived from the fusion of primary cells from adult human ventricular heart tissues with SV40 transformed, uridine auxotroph human fibroblasts, devoid of mitochondrial DNA . After selection in uridine-free medium to remove unfused fibroblasts, the resulting fused cells were further subcloned and subsequently screened for the presence of SV40 large T-ag, ?-myosin heavy chain (?MHC) and connexin-43 (CX-43) .AC16 cells are proliferating and differentiation of the cells may be controlled by altering culture conditions and by silencing the expression of SV40 T-Ag . The cells can be used to study cardiac gene expression and function, during normal development and in pathological conditions at the cellular, organellar and molecular levels.
Sinónimos : AC16 Ventricular Cardiomyocyte Cell Line; AC16 Ventricular Cardiomyocyte Cell Line
Armazenamento : liquid N2 (-196°C)
Embalagem : 1X1EA