Anti-Human IgM (mu-chain specific)-Peroxidase antibody produced in goat

REF : A6907-1ML
Marca : Sigma-Aldrich
Descrição :Anti-Human IgM (mu-chain specific)-Peroxidase antibody produced in goat affinity isolated antibody, buffered aqueous solution
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Descrição detalhada : Human IgM antibodies are glycoproteins that are mainly produced by the B-1 cells and regulate the physiology and growth of the human B cell reserve. Circulating monoclonal IgM antibody that binds to myelin-associated glycoprotein has been linked to the demyelination of peripheral nerves in humans . Anti-human IgM ?-chain specific?peroxidase antibody is specific for human IgM when tested against human IgA, IgG, IgM, Bence Jones ? and Lambda myeloma proteins., There are five immunoglobulin classes in humans. Out of these, immunoglobulin M (IgM) is a high molecular weight protein that has five to six subunits. IgM monomers are made of two heavy chains and two light chains connected by a disulfide bond. Human serum shows low concentration of IgM monomers. It has a high carbohydrate content of about 12%. It is the first immunoglobulin produced by neonates.
Sinónimos : Goat Anti-Human IgM (mu-chain specific)?HRP
Armazenamento : -20C
Embalagem : 1X1ML