Anti-beta-Actin-Peroxidase antibody, Mouse monoclonal

Descrição detalhada : In staining of chicken gizzard ultrathin tissue cryosections, the antibody labels the dense bodies and longitudinal channels linking consecutive dense bodies that are also occupied by desmin and the membrane-associated dense plaque. It does not stain adult cardiac and skeletal muscles except for traces due to contaminations of the sample with non-muscle cells, or if embryonic tissue is being used. , Mouse monoclonal anti-beta-actin-peroxidase antibody specifically localizes beta-actin in a wide variety of tissues and species using immunoblotting (42kDa). The antibody cross-reacts with beta-Actin expressed in cells of human, bovine, sheep, pig, rabbit, cat, dog, mouse, rat, guinea pig, chicken, carp, and Hirudo medicinalis (leech) tissues, but not in Dictyostelium discoideum amoebae or Drosophila., Actin is one of the most conserved eukaryotic proteins and is expressed in mammals and birds as at least six isoforms. There are three ?-actins (skeletal, cardiac, and smooth muscle), one ?-actin (?-nonmuscle), and two ?-actins (?-smooth muscle and ?-non muscle). Actin isoforms show >90% overall sequence homology, but only 50-60% homology in their NH2-terminal residues. ACTB (actin ?) gene codes for ?-actin. It is a cytoskeletal housekeeping protein. It is present in the cytoplasm. The ACTB gene is located on human chromosome 7p22.1.Mouse monoclonal anti-?-actin-peroxidase antibody specifically localizes ?-actin in a wide variety of tissues and species using immunoblotting (42kDa). The antibody cross-reacts with ?-Actin expressed in cells of human, bovine, sheep, pig, rabbit, cat, dog, mouse, rat, guinea pig, chicken, carp, and Hirudo medicinalis (leech) tissues, but not in Dictyostelium discoideum amoebae or Drosophila.
Sinónimos : Monoclonal Anti-beta-Actin; Loading Control
Armazenamento : -20C
Embalagem : 1X200UL