Anti-beta-Amyloid antibody, Mouse monoclonal

Descrição detalhada : The antibody reacts specifically with beta-amyloid protein. The epitope recognized by the antibody resides within amino acids 1-12 of the beta-amyloid protein. It specifically stains amyloid plaques within the cortex and amyloid deposits in blood vessels using formic acid-treated, formalin-fixed, paraffin-embedded, and Methacarn-fixed sections of human Alzheimer's disease (AD) brain tissue., ?-amyloid protein or a?4 is derived from larger protein that belongs to the family of 70kDa transmembrane glycoproteins (amyloid precursor proteins, APP). These are produced in various isoforms by alternative splicing. APPs are synthesized by many tissues including brain cells. Abnormal ?-amyloid protein deposits have been associated with Alzheimer?s disease, Down?s syndrome, Dutch-type amyloidosis and Lewy body dementia.
Sinónimos : Anti-beta-Amyloid antibody, Mouse monoclonal; Anti-A-BETA; Anti-Amyloid beta Precursor Protein; Clone BAM91
Armazenamento : -20C
Embalagem : 1X.2ML