Anti-ESRRB Antibody

Descrição detalhada : Steroid hormone receptor ERR2, also known as ERR beta-2 or Estrogen receptor-like 2 or Estrogen-related receptor beta (ERR-beta), and encoded by the gene name ESRRB or ERRB2 or ESRL2, was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells. Mutations in ESRRB have been associated with autosomal recessive deafness which is a form of non-syndromic deafness characterized by non-progressive, prelingual hearing loss.
Sinónimos : Steroid hormone receptor ERR2, ERR beta-2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA