Anti-TDP-43 Antibody, clone DB9

Descrição detalhada : TAR DNA-binding protein 43 (TDP-43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP-43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.
Sinónimos : TAR DNA-binding protein 43, TDP-43, TDP43, TAR DNA binding protein-43
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA