Anti-FANCJ/BACH1 Antibody, clone 2G7

Descrição detalhada : Bach1 and Bach2 constitute a subfamily of the basic region-leucine zipper family. Bach proteins form heterodimers with small Maf proteins, bind to the Maf recognition element (MARE) and repress target gene expression. Transcription regulator protein BACH2 mediates early B cell differentiation and is specifically expressed in pro and mature B-cells. This protein plays an important role in both the immunoglobulin class switch, oncogene-induced senescence, and somatic hypermutation.
Sinónimos : Fanconi anemia group J protein, Protein FACJ, ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BRCA1-interacting protein C-terminal helicase 1, BRCA1-interacting protein 1
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA