Anti-ABCG5, clone 1B5E10 Antibody

Descrição detalhada : ATP-binding cassette sub-family G member 5, also known as Sterolin-1, and encoded by the gene name ABCG5, plays an important role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. ABCG5 is localized too the membrane and is expressed in the liver, lower levels in the small intestine and colon. Mutations associated with ABCG5 is Sitosterolemia, which is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile.
Sinónimos : ATP-binding cassette sub-family G member 5, Sterolin-1, ABCG5
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA