Anti-trimethyl Histone H3 (Lys27), Alexa Fluor(R) 647 Conjugate Antibody

Descrição detalhada : Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-449.
Sinónimos : Histone H3.1t, H3/t, H3t, H3/g
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA